Study on evaluating biological properties of Ibuprofen gel

Study on evaluating biological properties of Ibuprofen gel

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Ibuprofen is a typical SIBERIAN GINSENG Non-Steroidal Anti-Inflammatory Drug (NSAID) commonly used to treat mild to moderate pain, inflammation, and fever.However, long-term oral use of ibuprofen for chronic diseases such as arthritis can cause serious side effects, including stomach ulcers.Therefore, a topical gel formula containing 5% ibuprofen, ethanol, propylene glycol, and poloxamer 407 has been researched and developed to solve the above problem.This article presents the results of the previously mentioned ibuprofen gel evaluation.As a result, according to ISO 10993:2009 (ISO, 2015) criteria, the given ibuprofen gel is not likely to be hazardous to L-929 mouse fibroblasts and hF human fibroblasts.

Furthermore, ibuprofen gel can distribute uniformly, release active substances from the Gel scaffold at a rate of more than 90% in 05 hours, and penetrate the skin of white mice.This study approach may be expanded with various research topics, such as assessing the capacity of active substances to permeate human 7 Piece Counter Dining Set skin, examining the amount of irritation, and assessing stability.